2023.2 Our group participated in the ASU Open Door this year to demonstrate our portable diagnostic technology. Hundreds of people from different parts of Arizona joined us to understand the science and had some hands-on practice of experiments. It was such a successful and fun experience!
2023.1 Abdulla Al Mamun and Nimarpreet Bamrah joined our lab as Ph.D. students. Abdulla received his B.Sc. in Electrical and Electronic Engineering Degree from Chittagong University of Engineering and Technology, Bangladesh in 2013 and his M.Sc. in Electrical Engineering from Washington State University in December 2022. Nimar completed her B.Sc. in 2018 and M.Sc. in physics in 2020, from Guru Nanak College, Sri Muktsar Sahib. She also worked with Indian Institute of Science (IISc), Bangalore, India in 2021. Abdulla and Nimar will work on nanofabrication, additive manufacturing, nanophotonics and biosensors. Welcome, Abdulla and Nimar!
2023.1 Dr. Faizan Ahmed joined our lab as a postdoctoral scholar. Faizan received his doctorate from IIIT Allahabad in 2021. His research interests include 2D films, heterostructures, nanoelectronics devices and Optoelectronics. Welcome, Faizan!
2023.1 Jiawei successfully defended his dissertation and will work with Dr. Yu Yao as a postdoctoral researcher at ASU. Congratulations, Dr. Zuo!
2022.11 Dr. Chao Wang delivered an invited talk on “Digital Biosensing with Nanoparticles for Infectious Diseases” to IEEE Nanotechnology Materials and Devices Conference.
2022.11 Shinhyuk successfully defended his dissertation and will start his next chapter at Samsung in Texas. Congratulations, Dr. Choi!
2022.9 We are awarded a NIH Director’s New Innovator award of >$2.2M from the The NIH Common Fund and National Institute Of General Medical Sciences (NIGMS) to develop an on-chip single-molecule protein sequencing (SMPS) technology. The research project will leverage our strengths in exploring multiple disciplines in engineering (nanofabrication, nanofluidics, photonic metasurface), biochemistry, and machine learning, to create a new platform that is rapid, inexpensive and versatile. SMPS of this kind holds the potential to revolutionize diagnostic medicine through the identification of protein biomarkers for cancer and other deadly diseases, provide earlier and more accurate diagnoses and deepen our understanding of how healthy cells function.
Please read the news release from ASU and NIH here:
ASU researcher advances the science of protein sequencing with NIH Innovator Award | ASU News
New Innovator Award Recipients (nih.gov)
2022.9 Pengkun successfully defended his dissertation and will continue his research as a postdoc researcher. Congratulations, Dr. Xia!
2022.9 Andrew Kemeklis continues his research on machine learning for nanopore data analysis as a master’s student.
2022.9 Eight (8) new undergrad students join our lab to do research on portable nanoparticle sensors, nanopore sensors and additive manufacturing, with seven (7) of them supported by NSF as REU students. Welcome, Scott Clemens, Najia Khan, Ji Yeon Lee, Kylie Peterson, Britney Hill, Abyssinia Bizuneh, Misa Lin Kalvelage, and Alexandra Krylova!
2022.8 Ashif successfully defended his dissertation, and started his new career at Intel in Oregon. Congratulations, Dr. Ikbal!
2022.7 Our lab hosted 4 SURI students: Andrew Kemeklis, Alexandra Krylova, Maria ‘Isa’ Tornelli , and Mugdhasrija R. Desai. Great job, team!
2022.5 We delivered 5 papers at EIPBN conference in New Orleans.
Chao Wang, “Nanotechnology for Infectious Disease Detection” (Invited Short Course)
Shinhyuk Choi, Zhi Zhao, Jiawei Zuo, Hossain Mansur Resalat Faruque, Yu Yao, and Chao Wang, “Color Printing by Polymer-Assisted Photochemical Deposition of Metallic Thin Films.” (Oral)
Jiawei Zuo, Jing Bai, Shinhyuk Choi, Ali Barsiri, Xiahui Chen, Chao Wang, and Yu Yao, “Chip-Integrated Full-Stokes Polarimetric Imaging Sensor” (Invited)
Pengkun Xia, Md Ashiqur Rahman Laskar, Xu Zhou, Deeksha Nolastname, Gde Bimananda Mahardika Wisna, Yinan Zhang, Rizal Hariadi, Hao Yan, and Chao Wang, “High-speed and High-resolution Readout of Multilevel Encoded DNA Origami by Sapphire-supported Nanopores”. (Oral)
Md Ashif Ikbal, Shoukai Kang, Xiahui Chen, Liangcai Gu, and Chao Wang, “Sensitive Optoelectronic Detection of Small Molecules Using Portable Metal Nanoparticle Readers” (Poster)
2022.5 We delivered 3 oral presentations at CLEO conference in San Jose.
Jiawei Zuo, Jing Bai, Shinhyuk Choi, Xiahui Chen, Chao Wang, and YuYao, “Chip-Integrated Full-Stokes Polarimetric Imaging Sensor.”
Shinhyuk Choi, Zhi Zhao, Jiawei Zuo, Hossain Mansur Resalat Faruque, Yu Yao, and Chao Wang, “3D Color Printing by Additive Manufacturing of Metallic Thin Films.”
Md Ashif Ikbal, Shoukai Kang, Xiahui Chen, Liangcai Gu, and Chao Wang, “Sensitive Optoelectronic Detection of Small Molecules Using Metal Nanoparticle Readers.”
2022.5 We are awarded a NIH R21 grant from the National Institute of Allergy and Infectious Diseases (NIAID) to develop a technology to rapidly detect and quantify the neutralizing antibodies against different SARS-CoV-2 variants. Such a technology would be very useful to identify the protection from new surging Omicron variants, which have shown great immunity-escape potential. This new research project is in collaboration with Dr. Neal Woodbury and Dr. Brenda Hogue at ASU.
Please read the abstract here:
2022.5 We are awarded $750k to combat African swine fever (ASF) disease in collaboration with Centro de Investigación en Sanidad Animal, CISA/INIA-CSIC, in Spain. This new research project is sponsored by the Agriculture and Food Research Initiative (AFRI) Competitive Grants Program from USDA/NIFA. Here is a new releases that provides a good review of the project.
Simple, inexpensive diagnostic technology to combat global threat of African Swine Fever | Biodesign Institute | ASU
2022.4 Shinhyuk’s work on “painting with light” has been published on Light: Science & Applications. You can learn more about this story:
Structural color printing via polymer-assiste | EurekAlert!
Printing with light (asu.edu)
2022.2 Our new diagnostic technology (Nano2RED) has been published on Biosensors and Bioelectronics. You can learn more about this story:
Fast and accurate nanosensors pinpoint infectious diseases | ASU News
New Nanosensor Assay Detects Viruses Like SARS-CoV-2 and Ebola (medscape.com)
Researchers make cheap, portable nanosensor for disease detection | KJZZ
Scientists want stop the next pandemic before it starts. Here are the tests they’re building to do it (yahoo.com)
The story is also covered by many other media outlets, including ASU Biodesign, ASU Fulton school, AZCentral, LabMedica, Verve Times, Technology Networks, Science Daily, Honest Columnist, The Science Times, MDLinx, Knowledia, Nanowerk, Medically Prime.Com, Mirage News, Phys.Org, Nano Market, RapidMicroMethods, NovLink.co, etc.
2021.8 Zhi’s paper on DNA-Origami assembled single emitters has been online published with Nano Research. Follow this link that provides full access to the paper through the Springer Nature Content Sharing Initiative.
2020.12 Xiahui Chen successfully defended his Ph.D. dissertation! He is the first Ph.D. graduate from our lab. Congratulations, Xiahui! Wish you the best in your next chapter.
2020.12 Pengkun’s paper on sapphire based nanopore sensors has been online published with Biosensors & Bioelectronics. https://authors.elsevier.com/a/1cCuk3PVtpkT%7Es This link provides full access to the paper until Jan, 2021.
The news coverage from ASU: https://news.asu.edu/20210128-using-sapphire-biosensing-new-way-shape-gemstone
2020.10 Dr. Wang delivers an invited talk at IEEE Nanotechnology Materials and Devices Conference on our recent research on sapphire supported low-noise nanopore sensors.
2020.8 Md Ashiqur Rahman Laskar joined our lab as a Ph.D. Student. Welcome, Ashiqur!
2020.8 Dr. Wang is supported by NSF for DNA based storage and readout technologies (https://www.nsf.gov/awardsearch/showAward?AWD_ID=2027215)
This SemiSynBio II award supports our collaboration with Prof. Hao Yan and Prof. Rizal Hariadi to explore the programmability of DNA nanostructures for the encryption keys, making it practically impossible to intercept and break the encryption. The research team will embed encrypted information in three-dimensional DNA origami nanostructures in the form of nanoscopic patterns. The high spatial resolution of DNA-PAINT (DNA-based point accumulation for imaging in nanoscopic topography) (<20 nm) and sapphire-supported nanopore sensors (<10 nm) will support high-density information decryption of intricate single-molecule patterns on the DNA origami, while enabling a fast readout speed of up to 1 MHz. The fast readout methods will employ deep-learning classification techniques for automated decryption and improved accuracy.
2020.4 Dr. Wang is supported by NSF to develop an new sapphire based nanopore device for low-noise DNA sensing.(https://www.nsf.gov/awardsearch/showAward?AWD_ID=2020464)
This NSF-BSF award supports our collaboration with Prof. Amit Meller at Technion to carry out fundamental research to create a significantly improved nanopore sensor platform that integrates low-optical background titanium oxide membranes on low-capacitance and hence low-electrical-noise sapphire. The research team will fabricate small and thin TiO2 membranes on sapphire, establish high-throughput manufacturing methods for both membrane formation and nanopore drilling, perform single-molecule DNA translocation, study the DNA-nanopore interaction, and analyze the data for methylation detection.
2020.4 Our paper (Printing continuous metal structures via polymer-assisted photochemical deposition ) in collaboration with Dr. Yu Yao has been published on Materials Today (Impact factor 24)
This work is also reported here on ASU Now.
2019.12 Dr. Wang and collaborator Dr. Yu Yao are supported by NSF to develop an additive manufacturing method to print silver structures with micrometer resolution and at ambient conditions for functional electronic and photonic applications.(https://www.nsf.gov/awardsearch/showAward?AWD_ID=1947753)
This award supports fundamental research to help develop a room-temperature AM process that enables high-resolution printing without thermal damage. The new process will utilize solution-based layer-by-layer deposition to produce highly reflective and highly conductive metal microstructures directly from soluble metal salts. The metallic microstructures produced by this process have wide applications in semiconductor electronics, energy, healthcare, biomedical, aerospace, soft robotics, and automotive industries.
2019.11 Dr. Wang and collaborator Dr. Yu Yao are supported by DOE to develop a polarimetric imaging system to attach to drones and deployed to evaluate the performance of concentrating solar-thermal power (CSP) collector systems.(https://www.energy.gov/eere/solar/seto-fy2019-concentrating-solar-thermal-power)
Measuring polarization has the potential to provide much richer information of objects than conventional optical imagers, which measure only intensity and color. The imaging systems will be small enough to attach to drones and be deployed to evaluate the performance of CSP collector systems. They can also be attached to CSP plant power towers. Autonomous imaging will reveal damage and soiling on collector mirrors and reduce errors in mirror alignment, resulting in improved efficiency.
2019.08 Our paper in collaboration with Dr. Hao Yan (Soft Robotics Programmed with Double Crosslinking DNA Hydrogels, link: https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.201905911) is accepted by Advanced Functional Materials (impact factor 15.6). Congratulations, Zhi!
2019.08 Our paper in collaboration with Dr. Yu Yao (On Chip-Integrated Plasmonic Flat Optics for Mid-Infrared Full-Stokes Polarization Detection, link: https://www.osapublishing.org/prj/abstract.cfm?uri=prj-7-9-1051) is accepted by Photonics Research (impact factor 5.5). Congratulations, Jing and others!
2019.08 Our paper in collaboration with Dr. Yu Yao (Nature-Inspired Chiral Metasurfaces for On-Chip Circularly Polarized Light Detection, link: https://www.nature.com/articles/s41377-019-0184-4) is accepted by Light: Science & Applications (a journal of Nature Publishing Group, impact factor 14.0). Congratulations, Ali and others!
2019.05 Our group presented at the EIPBN conference (http://www.eipbn.org/2019/). Zhi and Pengkun delivered five (5) oral presentations!
2019.04 Zhi’s paper (Photochemical synthesis of dendritic silver nano-particles for anti-counterfeiting, link: https://pubs.rsc.org/en/content/articlehtml/2019/tc/c9tc01473j) is accepted by Journal of Materials Chemistry C (Impact factor 6.6). Congratulations, Zhi!
2019.02 Dr. Wang is awarded the NSF CAREER award to investigate a new strategy towards early-stage cancer diagnostics using liquid biopsy on an integrated optofluidic chip. (https://nsf.gov/awardsearch/showAward?AWD_ID=1847324)
The research objective of this CAREER proposal is to validate the hypothesis that an integrated and multiplexed optofluidic platform can accurately detect exosomal miRNAs. In pursuit of this goal, a nanofluidic chip (ExoMiRChip) will be designed to functionally integrate label-free exosome purification, on-chip exosomal miRNA extraction, and plasmonic miRNA sensing. Theories and experiments will be combined to address fundamental challenges in achieving high-resolution and high-throughput exosome nanoparticle sorting, high-sensitivity and high-specificity miRNA detection, and multi-functional integration of nanofluidic systems.
2018.08 Dr. Wang and collaborator Dr. Yu Yao are supported by NSF to develop an ultracompact on-chip integrated metasurface polarimetric imager.(https://www.nsf.gov/awardsearch/showAward?AWD_ID=1809997)
It is no exaggeration to say that the development of imaging sensors has made profound impact on our life, from a smartphone camera to the most advanced medical imaging equipment, and even to space exploration. Detecting light polarization has been proven to be essential for various applications such as biomedical diagnostics, remote sensing, target detection and astronomy. Yet, despite the fact that the sensitivity, speed, pixel density and color range of image sensors have been continuously improved, the capability of full-polarization imaging, hasn’t been realized on monolithically integrated sensors. This project is to develop a chip-integrated imaging sensor array, or in another word, polarimetric imaging array, to detect not only light intensity and color but also the complete polarization state of light. Such a compact system can be further incorporated into many portable systems for clinic diagnostics, real time environmental monitoring network, or a smartphone polarimeter for field study and research. By integrating research and education, the project is aimed to inspire and cultivate the next-generation of scientists and engineers in nanophotonics and nanotechnology to address grand challenges in health, security, environmental issues and space exploration.
2018.07 Dr. Wang and collaborators Dr. Sefaattin Tongay and Dr. Yu Yao are supported by NSF to explore new strategies to integrate quantum emitter arrays in 2D artificial superlattices with nanophotonic structures towards room temperature quantum logic operations. (https://www.nsf.gov/awardsearch/showAward?AWD_ID=1838443)
Two-dimensional (2D) crystals are a new class of materials that measure only a few nanometers in thickness. Recent studies have shown that these materials offer unique advantages over other known materials, and that they hold the potential to make a large impact in new-generation electronics, energy conversion, and storage applications. When these 2D crystals are stacked onto each other they form a material known as a 2D Moire superlattice, which possesses an unusual physical properties that may enable quantum computation. Such materials could revolutionize current information technologies. This research aims to reach a fundamental understanding of the optical behavior of 2D Moire superlattices using advanced optical measurement techniques, as well as develop state-of-the-art fabrication techniques to create nanoscale devices for manipulation of quantum information. Particularly, this research explores the quantum optics of Moire quantum emitters (Moire-QEs) as single-photon emitters and their integration with Fano-dielectric metacavities, allowing manipulation of coherent states in quantum logic operations. The research activities have significant impact on training of next-generation researchers. Doctoral and master students, as well as undergraduates conduct all the necessary experiments, participating in hands-on research activities.
2018.04 Xiahui Chen presented his research “A Novel Plasmofluidic Nanoantenna for Ultrasensitive Biological Nanoparticle Detection” at MRS meeting.
2018.01 Shinhyuk Choi joins our group as a Ph.D. student. Welcome, Shinhyuk!
2017.07 Dr. Wang is supported by NSF to collaborate with researchers at Iowa State University to design a silicon based nano-opto-fluidic chip for rapid exosome profiling. (https://www.nsf.gov/awardsearch/showAward?AWD_ID=1711412)
Liquid biopsy has significant advantages over traditional tumor biopsies, because it is minimally invasive and uses biofluids, such as blood and urine, to diagnose cancer and other diseases in their early stages. Exosomes, which are actively secreted from cancer cells, carry molecular constituents of their originating cells. The goal of this project is to develop a new capability to rapidly screen and profile exosomes based on both molecular and size characteristics. This research will lead to a transformative change in exosome analysis by integrating two state-of-the-art technologies on a single silicon chip. In addition, this research will be integrated with education through adding new lab modules to existing undergraduate biomedical engineering minor program curriculum, recruiting female students, and providing summer internship opportunities to African-American students to participate in the project at Iowa State University, and developing a new undergraduate-level course related to nanobiotechnology at Arizona State University.
2017.7 Our paper “Plasmonic Vertically Coupled Complementary Antennas for Dual-Mode Infrared Molecule Sensing” has been accepted to publication by ACS Nano.
2017.4 Our poster entitled “Plasomonic Vertically Coupled Complementary Antennas for Dual-Mode Infrared Molecule Sensing” won the Best poster nominee in MRS 2017 meeting poster session ED10!
2017.4 Congratulations to Xiahui Chen for winning the NKT student award at MRS 2017 Spring meeting symposium ED10!
2017.2 Undergraduate student Connie Kwok from Barrett, the Honors College, joined our group. Welcome, Connie!
2017.1 Our paper “Wafer-scale integration of sacrificial nanofluidic chips for detecting and manipulating single DNA molecules” has been accepted to publication by Nature Communications.
2016.12 Dr. Zhi Zhao joined our group as a postdoctoral researcher. Welcome, Zhi!
2016.8 Graduate students Pengkun Xia and Pouya Amrollahi join our lab. Welcome!
2016.8 Our paper “Nanoscale Lateral Displacement Arrays for Separation of Exosomes and Colloids Down to 20nm” has been published online on Nature Nanotechnology and highlighted by a number of media:
http://www.livetradingnews.com/ibm-nyseibm-cancer-detection-10700.html#.V6EzZuxHanM
http://www.nextbigfuture.com/2016/08/ibm-lab-on-chip-can-sort-20-nanometer.html?
2016.6 Dr. Wang’s paper entitled “Nanoscale Lateral Displacement Arrays for Separation of Exosomes and Colloids Down to 20nm” has been accepted to publication on Nature Nanotechnology. In this work, we study exosomes to demonstrate the capability of a new technology, termed nanoDLD arrays, in separating and collecting bio-colloid for “liquid biopsies”. Exosomes are important biomarkers for detecting cancers and other diseases, because of their accessibility and molecular cargo correlating with the state of their cell source. We present nanoDLD technology to analyze, sort and collect exosomes based on their sizes (average 59 nm, ranging 20-140 nm), a necessary precursor for single-particle exosome analysis. This work was accomplished in collaboration with IBM T.J. Watson research center and Princeton University.
2016.5 Dr. Pravin Paudel joins our lab as a postdoc scholar. Pravin completed his Ph.D. in Chemistry at University of South Carolina. Welcome, Pravin!
2016.2 Graduate student Xiahui Chen joins our lab. Welcome, Xiahui!
2016.2 Dr. Wang is promoted as a tenure-track assistant professor.
2015.1 Dr. Wang joins ASU ECEE as a research assistant professor.
